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Scaling Up: Embracing a scientific approach to business

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In this episode of Vistage LIVE, Stephanie Christopher sits down with Mark Bregman, a distinguished global business leader with a rich background in technology strategy and entrepreneurship, delivering profound insights into leadership, innovation and strategic thinking.

Mark draws from his extensive experience across Fortune 500 companies and start-ups, discussing the importance of applying a scientific approach to scaling up, business strategy, and leadership. He explores the nuanced art of leading organisations, emphasising the critical balance between operational excellence and strategic vision.

Key takeaways for leaders in scaling up:

Challenge your thinking – Firstly leaders must recognise and overcome cognitive biases to make better decisions. By seeking diverse perspectives and consistently questioning assumptions, they can avoid decision-making pitfalls. As a result, businesses can scale more effectively.

Change is constant; adaptability is key – Since businesses that resist change risk stagnation, leaders should not fear disruption. Instead, they should view it as an opportunity to innovate and scale up strategically. Ultimately, adaptability is the key to long-term success.

Technology is a leadership tool, not a threatAI and automation should be used to enhance, not replace, human decision-making. Smart leaders integrate technology to streamline operations, improve efficiencies, and support scalable growth.

Strategy needs a long-term lens – Too often, businesses focus excessively on short-term gains, which can be detrimental to scaling up. Instead, sustainable success requires making strategic decisions that prepare organisations for future challenges and opportunities.

Culture drives success –In addition to strategy, a resilient and adaptable organisational culture fosters innovation and long-term scalability. Therefore, leaders should invest in developing teams that embrace collaboration, agility, and continuous learning.

In summary Mark argues that scaling up requires balancing operational excellence with strategic vision. Companies that integrate scientific thinking—experimenting, learning from failure, and iterating based on data—are better positioned for sustainable growth. By embracing change, leveraging technology, and fostering a strong company culture, leaders can drive long-term innovation and competitive advantage.

Why business leaders should listen

Ultimately, this episode equips CEOs and business owners with the mindset and tools needed to lead with confidence, embrace change, and scale their organisations effectively.


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